OK let me see if I got it right. They (Google) used an innovation made by Microsoft (08:57 – 09:29 of the video) in order to make their Neural Network better and then they used already established bioinformatic algorithms. So, this is how their NN is built. Correct? Did I miss anything? Then they run
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GENEVA (Reuters) – A proposed 100-km particle accelerator under Geneva has joined an international quest to develop the successor to the Large Hadron Collider to help unlock humankind’s knowledge of matter. FILE PHOTO: A general view of the Large Hadron Collider (LHC) experiment during a media visit at the Organization for Nuclear Research (CERN) in
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BREAKING AND ENTERING The Extraordinary Story of a Hacker Called Alien By Jeremy N. Smith 292 pp. Houghton Mifflin Harcourt. $28. When the F.B.I. warned the Democratic National Committee that hackers had broken into its system before the 2016 elections, the help desk dismissed it as a potential prank call. And when the Russians used
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When the Fukushima Daiichi Nuclear Power Plant began spewing radioactive particles after it was clobbered by a tsunami in March 2011Kaori Sakumafled. She bundled her infant and toddler into a car and left her husband and family in Koriyama, 44 miles west of the ruptured facility. “The truth is, I ran away,” she says. Confronting
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A 73-year-old woman presented to the dermatology clinic with an 11-month history of an evolving pruritic, erythematous rash on her thighs, buttocks, trunk, and axillae (Panel A). The rash initially consisted of pruritic annular lesions with central duskiness and was treated with prednisone and antihistamines without improvement. The rash evolved into polycyclic erythematous plaques during
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In a University of California, Irvine-led study, researchers found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases. The study was published recently in Cell Reports. The circadian clock operates within the body and
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Our body’s cells are constantly changing. But which of these changes are healthy developments and which lead to serious diseases? This is what LifeTime, a new transnational and interdisciplinary initiative of leading European researchers, aims to discover. The consortium is jointly coordinated by the Max Delbrück Center in Berlin and the Institut Curie in Paris,
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USP7 activation requires the C-terminal tail in cis The activation of USP7 requires interaction between the CD and the C-terminal peptide (see Fig. 1a for domain definitions and nomenclature). The details of this interaction were described in a recent crystal structure (PDB: 5JTV) of Ubl45 and CD36. This structure clarifies how the activating C-terminal peptide binds,
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Image-based data for a quantitative model selection approach It is currently impossible to obtain time-lapse data of kidney branching morphogenesis in utero. We therefore cultured the dissected wild type (Fig. 2a, Supplementary Movie 1) and mutant kidneys (Supplementary Movies 2, 3) under a fluorescent microscope and imaged the branching process once per hour (for details see “Methods”—Kidney cultures
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Citation: Dube D, Ahalawat N, Khandelia H, Mondal J, Sengupta S (2019) On identifying collective displacements in apo-proteins that reveal eventual binding pathways. PLoS Comput Biol 15(1): e1006665. https://doi.org/10.1371/journal.pcbi.1006665 Editor: Anders Wallqvist, US Army Medical Research and Materiel Command, UNITED STATES Received: July 3, 2018; Accepted: November 23, 2018; Published: January 15, 2019 Copyright: ©
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Abstract Modern optical imaging experiments not only measure single-cell and single-molecule dynamics with high precision, but they can also perturb the cellular environment in myriad controlled and novel settings. Techniques, such as single-molecule fluorescence in-situ hybridization, microfluidics, and optogenetics, have opened the door to a large number of potential experiments, which begs the question of
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design thinkingstoryblocks Over the past few years, design thinking has quickly gained momentum in the business world. Some of the world’s leading brands—the likes of Apple, Google, HBO, Samsung, World Bank, and General Electric—have embraced design thinking as a means of optimizing product innovation. At its core, design thinking is a methodology for creative problem
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Enlarge this image The China National Space Administration’s lunar lander, seen on Jan. 11. China National Space Administration/Xinhua News Agency/AP hide caption toggle caption China National Space Administration/Xinhua News Agency/AP A hint of a cotton plant is growing on the moon, inside China’s lunar lander, scientists in China say. Photos released on Tuesday by Chongqing
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As newborns, we enter the world by inhaling. In leaving, we exhale. (In fact, in many languages the word “exhale” is synonymous with “dying.”) Breathing is so central to life that it is no wonder humankind long ago noted its value not only to survival but to the functioning of the body and mind and
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Australia is sweltering through an intense heatwave this week that’s scorching the country from coast to coast with temperatures as high as 49.3 degrees Celsius (120.7 degrees Fahrenheit). In numerous locations, temperature records have already been broken, with minimum overnight temperatures in three towns of 33°C (91°F) showing even the night offers no escape from
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Social media is linked to depression—or not. First-person shooter video games are good for cognition—or they encourage violence. Young people are either more connected—or more isolated than ever. Such are the conflicting messages about the effects of technology on children’s well-being. Negative findings receive far more attention and have fueled panic among parents and educators.
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The Japanese neatness consultant has inspired millions to declutter. So why is getting your home Instagrammably neat so difficult, asks David H. Freeman Does an orderly mind follow an orderly home?Josie Ford By David H. Freeman A CLUTTER-free kitchen, living room or office resonates with a clean, graceful aesthetic. Neatness implies organisation and discipline. Stress and
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Posted by: RNA-Seq Blog in Splicing and Junction Mapping 8 hours ago 115 Views While the reconstruction of transcripts from a sample of RNA-Seq data is a computationally expensive and complicated task, the detection of splicing events from RNA-Seq data and a gene annotation is computationally feasible. This latter task, which is adequate for many
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MicroRNAs, the tiny bits of genetic material that regulate gene expression, play a significant – but poorly understood – role in controlling the differences between individual cells. Yale researchers have developed a technology that sheds light on the workings responsible for these differences – a breakthrough that could lead to new insights about cancer development.
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A total lunar eclipse in Berlin. Getty This weekend half of the globe will witness a glorious ‘Super Blood Wolf Moon’ total lunar eclipse. For North America and Central America, Sunday night is when to look. For much of South America and Western Europe, the spectacle will occur in the early hours on Monday. “It’s perfectly
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