Share to facebook Share to twitter Share to linkedin Drought conditions across the United States as of August 28, 2018.Dennis Mersereau Downpours this summer have felt like a zero-sum game. If someone’s getting a deluge, someone else in another part of the country is going another day without a drop of much-needed rainfall. Drought conditions
Just because you reject one fact with a staggering amount of common sense and scientific evidence behind it doesn’t mean you have to reject all of them – and so it is that Flat Earthers officially accept human-caused climate change. This week Reddit drew our attention to a tweet from the Flat Earth Society posted
Citation: Mets DG, Brainard MS (2018) An automated approach to the quantitation of vocalizations and vocal learning in the songbird. PLoS Comput Biol 14(8): e1006437. https://doi.org/10.1371/journal.pcbi.1006437 Editor: Dezhe Z. Jin, The Pennsylvania State University, UNITED STATES Received: August 4, 2017; Accepted: August 15, 2018; Published: August 31, 2018 Copyright: © 2018 Mets, Brainard. This is
Citation: Tzovara A, Korn CW, Bach DR (2018) Human Pavlovian fear conditioning conforms to probabilistic learning. PLoS Comput Biol 14(8): e1006243. https://doi.org/10.1371/journal.pcbi.1006243 Editor: Samuel J. Gershman, Harvard University, UNITED STATES Received: May 30, 2017; Accepted: May 29, 2018; Published: August 31, 2018 Copyright: © 2018 Tzovara et al. This is an open access article distributed
By Leah Crane Printers that use sound waves could one day let you build structures made out of honey droplets, or even print human tissue without damaging the cells. Regular inkjet printers are great at controlling the placement and size of droplets of ink, but they only work for thin, watery fluids. Daniele Foresti at
Some parts of the body – including the tissues of the brain and testes – have long been considered to be completely hidden from our immune system. In 2016 scientists made the amazing discovery that a set of previously unseen channels connected the brain to our immune system; but a 2017 discovery means we might
While the science our customers do is incredibly diverse, there are some common needs for all our users. They need software that is easy to use, to connect to their instruments and systems and to extend to new workflows. The latest version of Thermo Fisher™ Platform for Science™ software has been designed with all of…
Understanding the nuances of insect flight has enormous practical applications for improving drone flight capabilities A hawkmoth (Family: Sphingidae) hovers at a flower as it sips nectar through a proboscis that is longer than its body.(Credit: bioGraphic)bioGraphic The first time I ever saw a hawkmoth in the wild, I mistook it for a very small
HEIDELBERG, Germany (Reuters) – Armed with a mouse and computer screen instead of a scalpel and operating theater, cardiologist Benjamin Meder carefully places the electrodes of a pacemaker in a beating, digital heart. A three-dimensional printout of a human heart is seen at the Heidelberg University Hospital (Universitaetsklinikum Heidelberg) in Heidelberg, Germany, August 14, 2018.
One of the main benefits of using modern RNA-Sequencing (RNA-Seq) technology is the more accurate gene expression estimations compared with previous generations of expression data, such as the microarray. However, numerous issues can result in the possibility that an RNA-Seq read can be mapped to multiple locations on the reference genome with the same alignment
It has its directive: seek and destroy. And the underwater drone RangerBot is ready to put its lethal skills to work on Australia’s horrifically threatened Great Barrier Reef. But it’s not the coral that’s the target of its deadly focus. RangerBot is more like a bodyguard, trying to protect the reef from one of its
Milena Canning can see steam rising from a coffee cup but not the cup. She can see her daughter’s ponytail swing from side to side, but she can’t see her daughter. Canning is blind, yet moving objects somehow find a way into her perception. Scientists studying her condition say it could reveal secrets about how
Past experiments using CERN’s super-sized particle-smasher, the Large Hadron Collider (LHC), hinted at something unexpected. A particle called a beauty meson was breaking down in ways that just weren’t line up with predictions. That means one of two things – our predictions are wrong, or the numbers are out. And a new approach makes it
Some people recreationally partake in cannabis to free their minds. But the plant’s non-intoxicating compound, cannabidiol (CBD), might actually be able to help others rein their minds in. According to a new study from King’s College London (KCL), just one dose of CBD can reduce abnormal brain function in people with psychosis, a condition in
First, New Zealand declared war on dirty-clawed predators – stoats, rats, weasels – and there was little to be missed. But as the fight comes to the kitties, some owners are paws-sitively outraged. New Zealand’s efforts to protect its most rarefied creatures are turning to a measure that has rattled many cat owners: banning feline
A fruit that only grows in the Amazonian rainforest has shown a surprising effect. It’s called camu camu, and when its extract was fed to mice living on a high-fat, high-sugar diet, it seemed to slow weight gain – suggesting it could play a role in fighting obesity, according to researchers from Université Laval in
Cellular RNA levels are determined by transcription and decay rates, which are fundamental in understanding gene expression regulation. Measurement of these two parameters is usually performed independently, complicating analysis as well as introducing methodological biases and batch effects that hamper direct comparison. Researchers from Aarhus University present a simple approach of concurrent sequencing of S. cerevisiae
Social media went nuts on Wednesday night over a line of bright lights that appeared briefly in the sky over San Diego before vanishing. Reports came from far and wide, with shaky footage uploaded to Youtube and blurry pics shared across Twitter giving us plenty of images, but little information to go on. What are
In July of 2015, NASA’s New Horizons mission made history when it became the first spacecraft to conduct a flyby of Pluto. Since that time, the spacecraft’s mission was extended so it could make its way farther into the outer Solar System and become the first spacecraft to explore some Kuiper Belt Objects (KBOs). It’s
The small, tropical fish known as a cleaner wrasse has just joined the ranks of various mammals and birds that have passed a classic test for determining self-awareness. An international team of researchers have found the finger-sized wrasse are capable of recognising their reflection, suggesting some part of their brain must be aware of its
Saturn has been out there getting up to its old tricks again: looking really spectacular and being super interesting. This time, it’s in a series of photos taken by the Hubble Space Telescope, showing the planet’s breathtaking auroras. Over a period of seven months in 2017, the space-based telescope used its Space Telescope Imaging Spectrograph
It started with a late-night cough. “He was otherwise fine, but … something was weird and different,” said Verai Ramsammy, who was worried about her miniature schnauzer, Louie. She was a meticulous dog person, the kind who bought special food for her pets. She made a veterinary appointment just to be safe. Within months, Ramsammy’s
The International Space Station (ISS) is amazing. Floating 408 kilometres (254 miles) above us, astronauts get to do science experiments, and take great photos of Earth spinning beneath them. But it’s also tiny, a terrible place to poop, and occationally it springs leaks. On Wednesday at 23:00 UTC (19:00 EDT), flight controllers began to notice
Hilleman helped develop vaccines against several strains of the flu during his 40-year career in vaccine research. Jonas Salk gained worldwide fame for his polio vaccine; Louis Pasteur is remembered, among other things, for developing a vaccine against rabies, and Edward Jenner’s name is forever connected to vaccination against smallpox. But history barely remembers the
Detecting repeated cancer evolution from multi-region tumor sequencing data Detecting repeated cancer evolution from multi-region tumor sequencing data, Published online: 31 August 2018; doi:10.1038/s41592-018-0108-x REVOLVER uses transfer learning on multi-region tumor sequencing data to jointly infer tumor evolution models in multiple individuals and to detect repeated evolutionary trajectories. Repeated evolution can be used to stratify
Easing the burden of code review Easing the burden of code review, Published online: 31 August 2018; doi:10.1038/s41592-018-0137-5 Nature Methods is one of several Nature journals undertaking a trial with Code Ocean, a cloud-based reproducibility platform, to make it easier to peer review computational code.
Single-cell genomics to guide human stem cell and tissue engineering Single-cell genomics to guide human stem cell and tissue engineering, Published online: 31 August 2018; doi:10.1038/s41592-018-0113-0 A review of how single-cell sequencing methods can be used to improve human stem cell and tissue engineering.
CDeep3M—Plug-and-Play cloud-based deep learning for image segmentation CDeep3M—Plug-and-Play cloud-based deep learning for image segmentation, Published online: 31 August 2018; doi:10.1038/s41592-018-0106-z CDeep3M provides a user-friendly tool for deep-learning-based image segmentation via a cloud-based deep convolutional neural network. Demonstrations include challenging light, X-ray, and electron microscopy segmentation tasks.
The hepatocellular carcinoma market The hepatocellular carcinoma market, Published online: 31 August 2018; doi:10.1038/nrd.2018.146 The market for hepatocellular carcinoma is set to change with the recent approvals of the kinase inhibitor lenvatinib and the immune checkpoint inhibitor nivolumab, as well as the anticipated approvals of further immunotherapies.
Molecular mechanisms of CRISPR–Cas spacer acquisition Molecular mechanisms of CRISPR–Cas spacer acquisition, Published online: 31 August 2018; doi:10.1038/s41579-018-0071-7 In this Progress article, McGinn and Marraffini review recent studies that have advanced our understanding of the molecular mechanisms of spacer integration, protospacer capture and primed spacer acquisition, and discuss the future of the field.
A model of Toyota Motor Corp.’s Prius battery pack is displayed at Panasonic EV Energy Co.’s Omori plant in Kosei, central Japan, Friday, June 5, 2009. (AP Photo/Shizuo Kambayashi) Co-authors Austin Brown & Dan Sperling EV challenges remain but battery life is not one of them. There are lots of great reasons to drive electric. The modern
Abstract The mechanism of rapid energy supply to the brain, especially to accommodate the heightened metabolic activity of excited states, is not well-understood. We explored the role of glycogen as a fuel source for neuromodulation using the noradrenergic stimulation of glia in a computational model of the neural-glial-vasculature ensemble (NGV). The detection of norepinephrine (NE)
Abstract Workshops are used to explore a specific topic, to transfer knowledge, to solve identified problems, or to create something new. In funded research projects and other research endeavours, workshops are the mechanism used to gather the wider project, community, or interested people together around a particular topic. However, natural questions arise: how do we
Abstract The spikes on virus surfaces bind receptors on host cells to propagate infection. High spike densities (SDs) can promote infection, but spikes are also targets of antibody-mediated immune responses. Thus, diverse evolutionary pressures can influence virus SDs. HIV’s SD is about two orders of magnitude lower than that of other viruses, a surprising feature
Abstract Isolation profoundly influences social behavior in all animals. In humans, isolation has serious effects on health and disease. Drosophila melanogaster is a powerful model to study small-scale, temporally-transient social behavior. However, longer-term analysis of large groups of flies is hampered by the lack of effective and reliable tools. We built a new imaging arena
Citation: Raden M, Mohamed MM, Ali SM, Backofen R (2018) Interactive implementations of thermodynamics-based RNA structure and RNA–RNA interaction prediction approaches for example-driven teaching. PLoS Comput Biol 14(8): e1006341. https://doi.org/10.1371/journal.pcbi.1006341 Editor: Francis Ouellette, Genome Quebec, CANADA Published: August 30, 2018 Copyright: © 2018 Raden et al. This is an open access article distributed under the
Abstract Hysteresis, the discrepancy in forward and reverse pathways of state transitions, is observed during changing levels of consciousness. Identifying the underlying mechanism of hysteresis phenomena in the brain will enhance the ability to understand, monitor, and control state transitions related to consciousness. We hypothesized that hysteresis in brain networks shares the same underlying mechanism