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Share to facebook Share to twitter Share to linkedin Demis Hassabis, chief executive officer and co-founder of DeepMind Technologies Ltd., speaks during an event at Google’s Kings Cross office in London. Photographer: Simon Dawson/Bloomberg DeepMind is hiring someone to write speeches for its senior leadership team and “articulate the company’s mission and impact on the
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With the recent advances in DNA sequencing technologies, the study of the genetic composition of living organisms has become more accessible for researchers. Several advances have been achieved because of it, especially in the health sciences. However, many challenges which emerge from the complexity of sequencing projects remain unsolved. Among them is the task of
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Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance, Published online: 05 September 2018; doi:10.1038/s41568-018-0053-0 Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance
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Abstract Clustering of genes and/or samples is a common task in gene expression analysis. The goals in clustering can vary, but an important scenario is that of finding biologically meaningful subtypes within the samples. This is an application that is particularly appropriate when there are large numbers of samples, as in many human disease studies.
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Abstract Genomic data are becoming increasingly valuable as we develop methods to utilize the information at scale and gain a greater understanding of how genetic information relates to biological function. Advances in synthetic biology and the decreased cost of sequencing are increasing the amount of privately held genomic data. As the quantity and value of
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Abstract Forecasting the emergence and spread of influenza viruses is an important public health challenge. Timely and accurate estimates of influenza prevalence, particularly of severe cases requiring hospitalization, can improve control measures to reduce transmission and mortality. Here, we extend a previously published machine learning method for influenza forecasting to integrate multiple diverse data sources,
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Our cognitive powers peak in autumnAndrey Bandurenko / Alamy By Alison George Human cognitive powers have a seasonal rhythm, and for those living in temperate regions in the northern hemisphere they are strongest in late summer and early autumn. The effect is large enough to tip some older people over the diagnostic threshold for dementia
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Moon landing movie First Man fails to show the US flag being planted on the moon, angering some people. They’re living in the past, say Nicholas Borroz and Egemen Bezci Ryan Gosling as Neil Armstrong in First ManPictorial Press Ltd/Alamy By Nicholas Borroz and Egemen Bezci There is a fiery controversy about a new movie, First Man, which recounts NASA’s
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Daybreak at Gale CraterNASA The United States Geological Survey (USGS) are experts in mapping natural resources here on Earth. Recently, however, the agency began large-scale mapping of space resources for mining. The USGS has been fundamental in determining resources across the United States, from mapping oil fields offshore the Gulf of Mexico to understanding aquifer
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SANTIAGO (Reuters) – Amazon.com is in talks with Chile to house and mine massive amounts of data generated by the country’s giant telescopes, which could prove fertile ground for the company to develop new artificial intelligence tools. FILE PHOTO: The logo of the web service Amazon is pictured in this June 8, 2017 illustration photo. REUTERS/Carlos
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Posted by: RNA-Seq Blog in Workshops 8 hours ago 228 Views Session Dates Oct. 31 – Nov. 2, 2018 andNov. 14-16, 2018 Please note: This is one iteration spanning six days over two weeks. High-throughput sequencing techniques can rapidly provide a global picture of the processes within cells, allowing for accelerated discoveries in biology. As
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Polio, smallpox, hepatitis A and B are all serious viruses humanity learned to subdue with effective solutions. Even the flu, which can shift and mutate each year, has a vaccine. And yet, there’s no remedy for the lowly cold. That’s not for lack of trying, though. The hunt for a cure for the common cold
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As part of its Nutrition Innovation Strategy, which is aimed at reducing chronic disease through improved nutrition, the FDA is examining ways to modernize food standards for dairy products. Specifically, the agency is concerned about plant-based foods that have traditional dairy product terms such milk, cheese, and yogurt, in their names. For example, many products
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Historically, the majority of patients seen by palliative care specialists have been near the end of life, and the field of palliative care has emphasized the efficacy of opioids for alleviating pain in this context. Likewise, much of hospice and palliative medicine training focuses on the inpatient setting, and clinicians trained in this tradition are
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The US Preventive Services Task Force (USPSTF) has recently published recommendations on screening for syphilis infection in pregnant women. What Is Syphilis? Syphilis is a sexually transmitted infection caused by bacteria called Treponema pallidum. There are different stages of syphilis, and each stage has different symptoms. Primary syphilis occurs 2 or 3 weeks after infection,
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To the Editor Changing the P value threshold to .005 does not solve the issue of how to interpret P values.1 It simply shifts the burden of proof to require a more extreme difference. Uncertainty regarding the potential benefit of a therapy that demonstrated a clinically meaningful but now statistically nonsignificant result would increase.2 The
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For hundreds of years, the development of new medical treatments relied on “real-world” experience. Discoveries such as citrus fruit curing scurvy described in the 1700s or insulin as a treatment for diabetes in the 1920s long preceded the advent of the modern randomized clinical trial. What these diseases had in common was a reliable method
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A recently approved device can help some women with breast cancer avoid exposure to radioactive materials during sentinel lymph node biopsies. The Sentimag System, which uses magnetic detection to identify the sentinel lymph node, is indicated for women undergoing mastectomy. Testing sentinel lymph nodes indicates whether the cancer has spread beyond the breast and helps
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On August 17, 1968, 50 years ago, a report from Bangladesh described the successful use of an oral rehydration solution (ORS) to treat patients hospitalized in shock from cholera gravis.1 Untreated, severe cholera resulted in high mortality (approaching 40%) from dehydration and shock, but research in the 1940s demonstrated that mortality could be reduced with
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To the Editor Dr Sobieraj and colleagues1 investigated the efficacy of single maintenance and reliever therapy (SMART) for asthma exacerbations and symptom control in patients with persistent asthma. The systematic review and meta-analysis demonstrated that among patients aged 12 years or older, SMART was associated with a reduced risk of asthma exacerbations compared with the
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A literature review was performed to collect information for 18 RT-qPCR methods for dengue virus detection (see Table 1), while whole genome sequences were collected directly from the NCBI Virus Variation Resource [12]. Method performance was assessed based on an in silico workflow (see Fig. 1) that was applied on all available complete genomes for every
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Polyamine metabolism and cancer: treatments, challenges and opportunities Polyamine metabolism and cancer: treatments, challenges and opportunities, Published online: 04 September 2018; doi:10.1038/s41568-018-0050-3 This Review discusses new insights into molecular mechanisms that link the dysregulation of polyamine metabolism with carcinogenesis and strategies for targeting this pathway for cancer therapy.
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Biosynthetic capacity, metabolic variety and unusual biology in the CPR and DPANN radiations Biosynthetic capacity, metabolic variety and unusual biology in the CPR and DPANN radiations, Published online: 04 September 2018; doi:10.1038/s41579-018-0076-2 Candidate phyla radiation (CPR) bacteria and DPANN archaea are massive radiations of organisms recently identified. In this Analysis, Castelle et al. explore the
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Original Investigation Effect of a Loading Dose of Atorvastatin on MACE in Patients With ACS and Planned PCI Otavio Berwanger, MD, PhD; Eliana Vieira Santucci, RT; Pedro Gabriel Melo de Barros e Silva, MD, MHS, PhD; Isabella de Andrade Jesuíno, Pharm; Lucas Petri Damiani, MSc; Lilian Mazza Barbosa, RT; Renato Hideo Nakagawa Santos, Stat; Ligia Nasi Laranjeira, RT; Flávia de Mattos Egydio, BiolSc, MSc; Juliana Aparecida Borges de Oliveira, CN; Frederico Toledo Campo Dall Orto, MD; Pedro Beraldo
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