Share to facebook Share to twitter Share to linkedin Demis Hassabis, chief executive officer and co-founder of DeepMind Technologies Ltd., speaks during an event at Google’s Kings Cross office in London. Photographer: Simon Dawson/Bloomberg DeepMind is hiring someone to write speeches for its senior leadership team and “articulate the company’s mission and impact on the
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Sharks are some of the most notorious meat-eaters on the planet. And for a long time, scientists assumed that the vast majority of these marine creatures were solely carnivorous. The ocean, however, is full of surprises. Scientists have now discovered that one of the most common sharks in the world is actually an omnivore. A
Rocket launches are difficult. They’re expensive, they require an insane amount of fuel, their exhausts blast pollution into the atmosphere. One concept that seems straight out of science fiction could solve these problems: an elevator connecting Earth and space. And now Japanese engineers are about to start testing one. On September 11, a team from
Planck’s law of radiative heat transfer has held up well under a century of intense testing, but a new analysis has found it fails on the smallest of scales. Exactly what this means isn’t all that clear yet, but where laws fail, new discoveries can follow. Such a find wouldn’t just affect physics on an
From rainfall to wildfires, 2017 was a record-breaking year for natural disasters. In August and September, Hurricanes Harvey, Irma and Maria left behind a high death toll, drowned homes, and destroyed power lines. Hundreds of people died in earthquakes around the world, from Mexico to the Iran-Iraq border, and nearly 1,400 people were killed during
With the recent advances in DNA sequencing technologies, the study of the genetic composition of living organisms has become more accessible for researchers. Several advances have been achieved because of it, especially in the health sciences. However, many challenges which emerge from the complexity of sequencing projects remain unsolved. Among them is the task of
Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance, Published online: 05 September 2018; doi:10.1038/s41568-018-0053-0 Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance
Bacteria-primed T cells identified as culprit in glaucoma Bacteria-primed T cells identified as culprit in glaucoma, Published online: 05 September 2018; doi:10.1038/s41577-018-0063-x Bacterially primed T cells reactive against heat shock proteins enter the eye and cause neurodegeneration in glaucoma.
Abstract Clustering of genes and/or samples is a common task in gene expression analysis. The goals in clustering can vary, but an important scenario is that of finding biologically meaningful subtypes within the samples. This is an application that is particularly appropriate when there are large numbers of samples, as in many human disease studies.
Abstract Genomic data are becoming increasingly valuable as we develop methods to utilize the information at scale and gain a greater understanding of how genetic information relates to biological function. Advances in synthetic biology and the decreased cost of sequencing are increasing the amount of privately held genomic data. As the quantity and value of
Abstract Forecasting the emergence and spread of influenza viruses is an important public health challenge. Timely and accurate estimates of influenza prevalence, particularly of severe cases requiring hospitalization, can improve control measures to reduce transmission and mortality. Here, we extend a previously published machine learning method for influenza forecasting to integrate multiple diverse data sources,
Immunotherapy to unleash the immune system against prostate cancer may be a new treatment option for men with specific DNA defects in their cancer cells. Photo credit: Getty royalty free. New research published today in the Journal of Clinical Investigation, led by scientists at the Institute of Cancer Research in the UK and Dana-Farber Cancer
Our cognitive powers peak in autumnAndrey Bandurenko / Alamy By Alison George Human cognitive powers have a seasonal rhythm, and for those living in temperate regions in the northern hemisphere they are strongest in late summer and early autumn. The effect is large enough to tip some older people over the diagnostic threshold for dementia
Moon landing movie First Man fails to show the US flag being planted on the moon, angering some people. They’re living in the past, say Nicholas Borroz and Egemen Bezci Ryan Gosling as Neil Armstrong in First ManPictorial Press Ltd/Alamy By Nicholas Borroz and Egemen Bezci There is a fiery controversy about a new movie, First Man, which recounts NASA’s
Daybreak at Gale CraterNASA The United States Geological Survey (USGS) are experts in mapping natural resources here on Earth. Recently, however, the agency began large-scale mapping of space resources for mining. The USGS has been fundamental in determining resources across the United States, from mapping oil fields offshore the Gulf of Mexico to understanding aquifer
SANTIAGO (Reuters) – Amazon.com is in talks with Chile to house and mine massive amounts of data generated by the country’s giant telescopes, which could prove fertile ground for the company to develop new artificial intelligence tools. FILE PHOTO: The logo of the web service Amazon is pictured in this June 8, 2017 illustration photo. REUTERS/Carlos
Do you want $500? No, seriously, you can have it right now. Or, if you can hold off for a little while… you can actually have $1,000. So, what’s it going to be? As it turns out, the way you decide to answer this hypothetical question may in fact be a predictor of your earning
Posted by: RNA-Seq Blog in Workshops 8 hours ago 228 Views Session Dates Oct. 31 – Nov. 2, 2018 andNov. 14-16, 2018 Please note: This is one iteration spanning six days over two weeks. High-throughput sequencing techniques can rapidly provide a global picture of the processes within cells, allowing for accelerated discoveries in biology. As
Polio, smallpox, hepatitis A and B are all serious viruses humanity learned to subdue with effective solutions. Even the flu, which can shift and mutate each year, has a vaccine. And yet, there’s no remedy for the lowly cold. That’s not for lack of trying, though. The hunt for a cure for the common cold
A rare manifestation of syphilis can affect the eyes, mimicking a range of ocular disorders. If left untreated, it can lead to blindness – and, according to new research, this problem appears to be on the rise. Researchers from the University of Sao Paulo in Brazil and Flinders University in Australia analysed records from four
This is the second of a three-part series that examines our growing understanding of the scope and impacts of microplastics pollution. Mark Browne had a suspicion. He hoped the samples of dried blood taken from a blue mussel and placed under a special microscope would tell him if he was correct. As a fuzzy, three-dimensional
Last week astronauts on board the International Space Station (ISS) awoke to a worrying message from flight control. Hidden somewhere on board the ISS was a tiny pressure leak that was slowly allowing air to seep out of the spacecraft and into the abyss. The six astronauts on board were not in any imminent danger,
For a year, not a lot happened. In July 2017, the world’s sixth-largest iceberg on record tore free from its Antarctic moorings after months of dramatic anticipation, in which the world watched a gigantic chasm split the Larsen C ice shelf in two. But then, this colossal broken shard of ice basically hunkered down. Satellite
Tropical Storm Gordon is centered 50 miles (80 kilometres) off the coast of Fort Myers, Florida on Monday evening, dumping rain on the peninsula and whipping its shores with maximum winds up to 50 miles per hour (80 km/h). Heading northwest at 17 miles per hour (27 km/h), the National Hurricane Center predicts Gordon could
Nearly 1 in 8 couples in the U.S. face infertility, and about half of those cases can be attributed to semen abnormalities in the male partner. As the root causes often remain a mystery, new research into the basic biology behind sperm development could one day lead to renewed hope for people wanting to
There are a lot of space maps out there, but we’d be willing to bet there’s never been one quite like this. It’s entirely knitted out of yarn, using a 1980s domestic knitting machine brilliantly turned into a network printer. The genius behind it is Australian software engineer Sarah Spencer, who used a Raspberry Pi,
If you happen to be visiting one of Utah’s many remote mountain lakes, don’t be alarmed if you suddenly see more fish in the sky than in the water. It’s not a trick of the eye. It’s the state’s latest attempt at trout restoration. The US state of Utah is well-known for excellent trout fishing in
Scientists say microwave signals may have caused brain injuries to 33 US officials and their family members at embassies in Cuba and China. The saga began in 2016 when 24 US diplomats and their family members fell ill after being exposed to what US officials claim was some form of “sonic attack”. The victims suffered
As part of its Nutrition Innovation Strategy, which is aimed at reducing chronic disease through improved nutrition, the FDA is examining ways to modernize food standards for dairy products. Specifically, the agency is concerned about plant-based foods that have traditional dairy product terms such milk, cheese, and yogurt, in their names. For example, many products
Historically, the majority of patients seen by palliative care specialists have been near the end of life, and the field of palliative care has emphasized the efficacy of opioids for alleviating pain in this context. Likewise, much of hospice and palliative medicine training focuses on the inpatient setting, and clinicians trained in this tradition are
The US Preventive Services Task Force (USPSTF) has recently published recommendations on screening for syphilis infection in pregnant women. What Is Syphilis? Syphilis is a sexually transmitted infection caused by bacteria called Treponema pallidum. There are different stages of syphilis, and each stage has different symptoms. Primary syphilis occurs 2 or 3 weeks after infection,
On May 30, 2018, President Trump signed into law the federal Right to Try Act of 2017,1 providing patients with life-threatening conditions a pathway to access investigational drugs without authorization from the Food and Drug Administration (FDA). Ethicists, physicians, and patient groups have raised concerns about this type of legislation at the state and national
To the Editor Changing the P value threshold to .005 does not solve the issue of how to interpret P values.1 It simply shifts the burden of proof to require a more extreme difference. Uncertainty regarding the potential benefit of a therapy that demonstrated a clinically meaningful but now statistically nonsignificant result would increase.2 The
For hundreds of years, the development of new medical treatments relied on “real-world” experience. Discoveries such as citrus fruit curing scurvy described in the 1700s or insulin as a treatment for diabetes in the 1920s long preceded the advent of the modern randomized clinical trial. What these diseases had in common was a reliable method
A recently approved device can help some women with breast cancer avoid exposure to radioactive materials during sentinel lymph node biopsies. The Sentimag System, which uses magnetic detection to identify the sentinel lymph node, is indicated for women undergoing mastectomy. Testing sentinel lymph nodes indicates whether the cancer has spread beyond the breast and helps
On August 17, 1968, 50 years ago, a report from Bangladesh described the successful use of an oral rehydration solution (ORS) to treat patients hospitalized in shock from cholera gravis.1 Untreated, severe cholera resulted in high mortality (approaching 40%) from dehydration and shock, but research in the 1940s demonstrated that mortality could be reduced with
Read alignment algorithm In our de Bruijn graph representation, linear paths of connected k-mers are contracted to unitigs. Nodes thus represent sequences of length k or larger. The problem of finding an optimal read alignment in a graph can be formalized as finding the optimal walk in that graph. A walk is an alternating list
To the Editor Dr Sobieraj and colleagues1 investigated the efficacy of single maintenance and reliever therapy (SMART) for asthma exacerbations and symptom control in patients with persistent asthma. The systematic review and meta-analysis demonstrated that among patients aged 12 years or older, SMART was associated with a reduced risk of asthma exacerbations compared with the
A literature review was performed to collect information for 18 RT-qPCR methods for dengue virus detection (see Table 1), while whole genome sequences were collected directly from the NCBI Virus Variation Resource [12]. Method performance was assessed based on an in silico workflow (see Fig. 1) that was applied on all available complete genomes for every
Polyamine metabolism and cancer: treatments, challenges and opportunities Polyamine metabolism and cancer: treatments, challenges and opportunities, Published online: 04 September 2018; doi:10.1038/s41568-018-0050-3 This Review discusses new insights into molecular mechanisms that link the dysregulation of polyamine metabolism with carcinogenesis and strategies for targeting this pathway for cancer therapy.
Biosynthetic capacity, metabolic variety and unusual biology in the CPR and DPANN radiations Biosynthetic capacity, metabolic variety and unusual biology in the CPR and DPANN radiations, Published online: 04 September 2018; doi:10.1038/s41579-018-0076-2 Candidate phyla radiation (CPR) bacteria and DPANN archaea are massive radiations of organisms recently identified. In this Analysis, Castelle et al. explore the
Original Investigation Effect of a Loading Dose of Atorvastatin on MACE in Patients With ACS and Planned PCI Otavio Berwanger, MD, PhD; Eliana Vieira Santucci, RT; Pedro Gabriel Melo de Barros e Silva, MD, MHS, PhD; Isabella de Andrade Jesuíno, Pharm; Lucas Petri Damiani, MSc; Lilian Mazza Barbosa, RT; Renato Hideo Nakagawa Santos, Stat; Ligia Nasi Laranjeira, RT; Flávia de Mattos Egydio, BiolSc, MSc; Juliana Aparecida Borges de Oliveira, CN; Frederico Toledo Campo Dall Orto, MD; Pedro Beraldo
The Tangled Shore, part of The Reef.Bungie Destiny 2’s massive new expansion – Forsaken – appears to largely take place in a part of the Solar System known as The Reef. It’s a rather chaotic, lawless, grit-in-your-teeth locale, which makes it an ideal setting for a tale of sci-fi flavored Western-tinged revenge. It’s not merely
The aftershocks of a devastating earthquake can often be as horrifying as the main event. Now scientists have developed a system for predicting where such post-quake tremors could take place, and they’ve used an ingenious application of artificial intelligence (AI) to make this happen. Knowing more about what’s coming next can be a matter of
Share to facebook Share to twitter Share to linkedin The forecast track for Gordon.NOAA It’s nothing like the destruction that Hurricanes Harvey and Irma wrought about a year ago, but Tropical Storm Gordon is currently drenching parts of Florida as it threatens to strengthen into a Hurricane on its way towards the coastlines of Louisiana,
Satellite images show the recovery of Yellowstone National Park following its most intense fire season in history. 30 years after the spectacular Yellowstone fires of 1988, recovery is nearly complete.NASA Visualization Explorer / SVS The past few years have brought some devastating wildfires to large parts of the American west. A wildfire as seen from
Europa is an icy moon of JupiterNASA/JPL-Caltech/SETI Institute By Leah Crane There is a weird cold spot on Europa, and nobody knows what it is. The first full thermal map of Jupiter’s icy moon has thrown up one spot about 300 kilometres across that seems colder than it ought to be, and we don’t have
The human genome may contain up to 20 percent fewer coding genes than scientists previously estimated, according to indications from new research. Ever since the Human Genome Project was completed in 2003, scientists have been trying to figure out how many of our genes are the functional variety that produce the proteins making up our
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