TissueEnrich – Tissue-specific gene enrichment analysis


in Pathway Analysis

4 hours ago

RNA-Seq data analysis results in lists of genes that may have a similar function, based on differential gene expression analysis or co-expression network analysis. While tools have been developed to identify biological processes that are enriched in the genes sets, there remains a need for tools that identify enrichment of tissue-specific genes.

Iowa State University researchers have developed TissueEnrich, a tool that calculates tissue-specific gene enrichment in an input gene set. They demonstrated that TissueEnrich can assign tissue identities to single cell clusters and differentiated embryonic stem cells.


Availability – The TissueEnrich web application is freely available at http://tissueenrich.gdcb.iastate.edu/. The R package is available through Bioconductor at https://bioconductor.org/packages/TissueEnrich. Both the web application and R package are for non-profit academic use under the MIT license.

Jain A, Tuteja G. (2018) TissueEnrich: Tissue-specific gene enrichment analysis. Bioinformatics [Epub ahead of print]. [abstract]

Articles You May Like

Ten simple rules for collaboratively writing a multi-authored paper
Scientists have found rare giant viruses lurking in the soil of a US forest
This Italian supervolcano looks to have restarted its deadly cycle of fire
‘We trust our rocket’, crew says ahead of first space launch since failure
Computational discovery of direct associations between GO terms and protein domains

Leave a Reply

Your email address will not be published. Required fields are marked *