FLIRT: fast local infrared thermogenetics for subcellular control of protein function

Methods

FLIRT: fast local infrared thermogenetics for subcellular control of protein function

FLIRT: fast local infrared thermogenetics for subcellular control of protein function, Published online: 30 October 2018; doi:10.1038/s41592-018-0168-y

FLIRT enables spatiotemporally precise control of protein function in C. elegans by harnessing existing temperature-sensitive mutations. Proteins can be inactivated at desired sites by infrared laser light targeted to the region(s) of interest.

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