Delivery of the gut microbiome Delivery of the gut microbiome, Published online: 17 July 2018; doi:10.1038/s41579-018-0059-3 Two studies characterize the transmission of the microbiome from mother to infant during the first months of life.
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Instructive power of senescence Instructive power of senescence, Published online: 17 July 2018; doi:10.1038/s41580-018-0042-x Senescent cells secrete a multitude of factors that modulate their local environment — a phenomenon known as senescence-associated secretory phenotype (SASP). David Bernard highlights that the SASP secretome can be flexibly regulated, resulting in different types of SASP, which contributes to
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1. Gray, M. W. & Archibald, J. M. in Genomics of Chloroplasts and Mitochondria, Advances in Photosynthesis and Respiration (eds Bock, R. & Knoop, V.) 1–30 (Springer, 2012). 2. Burton, R. S. & Barreto, F. S. A disproportionate role for mtDNA in Dobzhansky-Muller incompatibilities? Mol. Ecol. 21, 4942–4957 (2012). This review argues for a special
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Kentville Clock Time Travel.Rodger Evans (CC BY-ND 2.0) In our everyday lives, things seem to happen in a particular order. Things that happen to us seem to be triggered by earlier events. The upset stomach we have in the evening is caused by that third taco we had at lunch. Doing well on a final
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WASHINGTON (Reuters) – Charred remains of a flatbread baked about 14,500 years ago in a stone fireplace at a site in northeastern Jordan have given researchers a delectable surprise: people began making bread, a vital staple food, millennia before they developed agriculture. Amaia Arranz-Otaegui, a University of Copenhagen postdoctoral researcher in archaeobotany, and Ali Shakaiteer,
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You’ve heard the numbers: More than half of the world’s people now live in cities, and in just a few decades more than two thirds of the globe’s rapidly growing population will be urban. Because cities already suck up much of the planet’s resources and generate much of its waste, these trends threaten to make
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Some half a million people worldwide with severe hearing loss use an electronic implant in the ears to be able to let them understand speech. Cochlear implants, as they are known, are one of the most successful technologies to have come out of neuroscience, but only provide partial correction for any hearing deficit. They are
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Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.
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Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.
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High-precision automated reconstruction of neurons with flood-filling networks High-precision automated reconstruction of neurons with flood-filling networks, Published online: 16 July 2018; doi:10.1038/s41592-018-0049-4 Flood-filling networks are a deep-learning-based pipeline for reconstruction of neurons from electron microscopy datasets. The approach results in exceptionally low error rates, thereby reducing the need for extensive human proofreading.
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An enhanced CRISPR repressor for targeted mammalian gene regulation An enhanced CRISPR repressor for targeted mammalian gene regulation, Published online: 16 July 2018; doi:10.1038/s41592-018-0048-5 The fusion of dead Cas9 with KRAB and the transcriptional repressor domain of the chromatin modifier MeCP2 leads to an efficient transcriptional silencer that can be applied to genome-scale screens and
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A synthetic-diploid benchmark for accurate variant-calling evaluation A synthetic-diploid benchmark for accurate variant-calling evaluation, Published online: 16 July 2018; doi:10.1038/s41592-018-0054-7 The synthetic-diploid (Syndip) benchmark dataset, constructed from two fully homozygous long-read assemblies, provides more accurate assessments of error rates in small-variant-calling algorithms than existing benchmarks.
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Active PSF shaping and adaptive optics enable volumetric localization microscopy through brain sections Active PSF shaping and adaptive optics enable volumetric localization microscopy through brain sections, Published online: 16 July 2018; doi:10.1038/s41592-018-0053-8 Active PSF shaping and adaptive optics are combined to enable 3D localization microscopy throughout thick tissues. The method was used to study the
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Landing 12 people on the Moon remains one of NASA’s greatest achievements, if not the greatest. Astronauts collected rocks, took photos, performed experiments, planted some flags, and then came home. But those week-long stays during the Apollo program didn’t establish a lasting human presence on the Moon. More than 45 years after the most recent
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An actor-patient, made up to look as if he is infected with smallpox, is wheeled in an isolation pod during a drill at the Nebraska biocontainment unit in Omaha, Nebraska. (AP Photo/Nati Harnik) “You have smallpox,” are 3 words that you never want to hear, regardless of whether the “you” is you or any other
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KUALA LUMPUR (Reuters) – Manny Pacquiao put on a dominant display to stun defending champion Lucas Matthysse with a seventh-round knockout and claim the WBA welterweight title in Kuala Lumpur on Sunday. Boxing – WBA Welterweight Title Fight – Manny Pacquiao v Lucas Matthysse – Axiata Arena, Kuala Lumpur, Malaysia – July 15, 2018 Manny
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MOSCOW (Reuters) – Belgium will be acclaimed at celebrations in Brussels on Sunday with thousands expected to hail the team but they will carry mixed feelings about their achievement at the World Cup. Soccer Football – World Cup – Third Place Play Off – Belgium v England – Saint Petersburg Stadium, Saint Petersburg, Russia –
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More than 200,000 stars appear in this test image from TESS.Credit: NASA / MIT / TESS TESS—the new planet-hunting probe—is up, running, and almost ready to rumble. The robotic spacecraft, launched 12 weeks ago, is now locked into “final science orbit,” says NASA’s Padi Boyd. So far, all is good. Everything on TESS checks out,
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Share to facebook Share to twitter Share to linkedin A picture taken on July 13, 2018 shows an iceberg behind houses and buildings after it grounded outside the village of Innarsuit, an island settlement in the Avannaata municipality in northwestern Greenland. (KARL PETERSEN/AFP/Getty Images) From the right angle, the tiny village of Innaarsuit looks a
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Bacterial adhesion at the single-cell level Bacterial adhesion at the single-cell level, Published online: 15 July 2018; doi:10.1038/s41579-018-0057-5 In this Review, Brun and colleagues summarize our understanding of the mechanisms governing bacterial adhesion at the single-cell level, including the physical forces experienced by a cell before reaching the surface, the first contact with a surface
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Structural insights into the signalling mechanisms of two-component systems Structural insights into the signalling mechanisms of two-component systems, Published online: 15 July 2018; doi:10.1038/s41579-018-0055-7 Canonical two-component systems catalyse autophosphorylation of the histidine kinase, transfer of the phosphoryl group to the regulator and dephosphorylation of the phosphoregulator. In this Progress article, Jacob-Dubuisson and colleagues highlight recent
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Medieval Studies has a choice to make. Just this week controversy erupted over the largest annual academic conference devoted to the study of the Middle Ages in all of its forms – the International Congress on Medieval Studies (ICMS), hosted by Western Michigan University in Kalamazoo, Michigan. Many academic conferences in the Humanities and Social Sciences work
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Eight critically endangered black rhinoceroses died after being moved from parks near Kenya’s capital to a sanctuary in a national park in the country’s southeast, the government said Friday. Preliminary investigations suggest the rhinos suffered from salt poisoning as they adapted to water with higher saline levels than they were accustomed to, according to tourism
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This NASA/ESA Hubble Space Telescope image shows a massive galaxy cluster, PLCK_G308.3-20.2, glowing brightly in the darkness. This is what huge swaths of the distant Universe looks like. But how far does the Universe as-we-know-it, including the unobservable part, go on for?ESA/Hubble & NASA, RELICS; Acknowledgement: D. Coe et al. 13.8 billion years ago, the
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