A new era for understanding amyloid structures and disease

Reviews

A new era for understanding amyloid structures and disease

A new era for understanding amyloid structures and disease, Published online: 20 September 2018; doi:10.1038/s41580-018-0060-8

The aggregation of proteins into amyloid fibrils and their deposition into plaques and intracellular inclusions is the hallmark of amyloid disease. Recent advances in structural biology techniques have provided insight into how amyloid structure may affect the ability of fibrils to spread in a prion-like manner and into their roles in disease.

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