N6-mA marks the spot

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N6-mA marks the spot

<i>N</i><sup>6</sup>-mA marks the spot, Published online: 19 November 2018; doi:10.1038/s41568-018-0085-5

Xie et al. have shown that a recently reported DNA modification in mammals, repressive N6-methyladenine, is enriched in human glioblastoma and targeting this modification can reduce cancer cell growth by restricting chromatin accessibility at oncogenic loci.

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