Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

Reviews

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases, Published online: 22 November 2018; doi:10.1038/s41583-018-0093-1

Necroptosis is a form of cell death mediated by receptor-interacting protein kinase 1 (RIPK1), and is observed in several CNS disorders. Here, Yuan, Amin and Ofengeim give an overview of necroptosis in the CNS and explain its relationship with inflammation in CNS disorders.

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