New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer

Reviews

New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer

New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer, Published online: 20 November 2018; doi:10.1038/s41580-018-0080-4

Epithelial–mesenchymal transition (EMT) is crucial for embryogenesis, wound healing and cancer development, and confers greater resistance to cancer therapies. This Review discusses the mechanisms of EMT and its roles in normal and neoplastic tissues, the contribution of cell-intrinsic signals and the microenvironment to inducing EMT, and its effects on the immunobiology of carcinomas.

Articles You May Like

You’re Probably Not as Bad at Math as You Think. You Might Just Be Traumatised
A Surgeon Reflects On Death, Life And The ‘Incredible Gift’ Of Organ Transplant
Shifting north magnetic pole forces unprecedented navigation fix
Ovarian cancer AI can tell how aggressive a woman’s tumour is
Sodium in the microenvironment regulates immune responses and tissue homeostasis

Leave a Reply

Your email address will not be published. Required fields are marked *