Nonsense-mediated RNA decay in the brain: emerging modulator of neural development and disease

Reviews

Nonsense-mediated RNA decay in the brain: emerging modulator of neural development and disease

Nonsense-mediated RNA decay in the brain: emerging modulator of neural development and disease, Published online: 08 November 2018; doi:10.1038/s41583-018-0079-z

Nonsense-mediated RNA decay — a highly selective and conserved RNA turnover pathway — is shown to have roles in both brain development and function. In this Review, Jaffrey and Wilkinson discuss how this pathway affects the nervous system.

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