Therapeutic approaches to Huntington disease: from the bench to the clinic

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Therapeutic approaches to Huntington disease: from the bench to the clinic

Therapeutic approaches to Huntington disease: from the bench to the clinic, Published online: 21 September 2018; doi:10.1038/nrd.2018.133

New therapies, including RNA-based and gene therapies, are poised to change the therapeutic landscape for Huntington disease. In this article, Hayden and colleagues review the progress that has been made in the past 25 years in developing therapies for this disease and highlight the pitfalls and potential of future treatments.

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