Central CD4+ T cell tolerance: deletion versus regulatory T cell differentiation

Central CD4+ T cell tolerance: deletion versus regulatory T cell differentiation

Central CD4<sup>+</sup> T cell tolerance: deletion versus regulatory T cell differentiation, Published online: 12 November 2018; doi:10.1038/s41577-018-0083-6

Self-antigen recognition in the thymus can result in both clonal deletion of developing thymocytes and their diversion into the regulatory T cell lineage. How do thymocyte-intrinsic and thymocyte-extrinsic determinants influence this cell fate choice?

Articles You May Like

Giant X-ray ‘chimneys’ are exhaust vents for vast energies produced at Milky Way’s center
U.S. Mathematician Becomes First Woman To Win Abel Prize, ‘Math’s Nobel’
Kicking neural network automation into high gear
Grow a better jawbone in your ribs
Trying To Do Good

Leave a Reply

Your email address will not be published. Required fields are marked *