Fasting and cancer: molecular mechanisms and clinical application

Fasting and cancer: molecular mechanisms and clinical application, Published online: 16 October 2018; doi:10.1038/s41568-018-0061-0

This Opinion discusses the potential of fasting and fasting-mimicking diets to help overcome toxicities induced by anticancer therapy. The differential response of normal and cancer cells undergoing starvation is argued to make normal cells less sensitive to therapy-induced toxicity, while cancer cells become more sensitive to therapy-induced cell death.

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