Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes

Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes

Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes, Published online: 18 October 2018; doi:10.1038/s41580-018-0071-5

The distribution of lipids largely depends on their non-vesicular transport by lipid transfer proteins (LTPs). Recent progress in understanding the mechanisms of LTPs, including the appreciation of their widespread activity at membrane contact sites, has provided novel insights into the regulation of lipid trafficking and how it impacts pathophysiology.

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