Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging

Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging

Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging, Published online: 20 August 2018; doi:10.1038/s41592-018-0105-0

Slow off-rate modified aptamer (SOMAmer) reagents are small and versatile probes for DNA-PAINT super-resolution microscopy that enable multiplexed, quantitative, and high-resolution imaging in fixed and live cells.

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