mRNA alterations mimic genetic mutations

mRNA alterations mimic genetic mutations

mRNA alterations mimic genetic mutations, Published online: 21 September 2018; doi:10.1038/s41568-018-0059-7

Lee, Singh et al. find that cancer-specific intronic polyadenylation events occur frequently in tumour suppressor genes in chronic lymphocytic leukaemia (CLL) and generate truncated proteins that could act as CLL drivers.

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