Post-GWAS in prostate cancer: from genetic association to biological contribution

Post-GWAS in prostate cancer: from genetic association to biological contribution

Post-GWAS in prostate cancer: from genetic association to biological contribution, Published online: 11 December 2018; doi:10.1038/s41568-018-0087-3

This Review discusses causal germline variants in prostate cancer identified through genome-wide association studies (GWAS) and post-GWAS analyses. The latter are vital to identify causal variants and molecular mechanisms by which these variants promote prostate tumorigenesis, with potential clinical applications.

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