Regulation of microRNA biogenesis and its crosstalk with other cellular pathways

Regulation of microRNA biogenesis and its crosstalk with other cellular pathways

Regulation of microRNA biogenesis and its crosstalk with other cellular pathways, Published online: 18 September 2018; doi:10.1038/s41580-018-0059-1

The cleavage of microRNA (miRNA) precursors by Drosha and Dicer and their loading with Argonaute proteins into RNA-induced silencing complexes are key steps in miRNA biogenesis. Recent studies have clarified the mechanisms of action of these molecular machines and discovered non-canonical miRNA biogenesis pathways.

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