Therapeutically exploiting STAT3 activity in cancer — using tissue repair as a road map

Therapeutically exploiting STAT3 activity in cancer — using tissue repair as a road map

Therapeutically exploiting STAT3 activity in cancer — using tissue repair as a road map, Published online: 21 December 2018; doi:10.1038/s41568-018-0090-8

This Review discusses how excessive signal transducer and activator of transcription 3 (STAT3) activation within cancer cells and cells of the tumour microenvironment can be viewed as a neoplastic mimic of an inflammation-driven repair response that promotes tumour progression.

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