Towards quantitative and multiplexed in vivo functional cancer genomics

Towards quantitative and multiplexed in vivo functional cancer genomics

Towards quantitative and multiplexed in vivo functional cancer genomics, Published online: 28 September 2018; doi:10.1038/s41576-018-0053-7

CRISPR–Cas genome editing and next-generation sequencing are driving advances in cancer modelling and functional cancer genomics. Their application to autochthonous mouse models of human cancer to generate and analyse multiplexed and/or combinatorial alterations in vivo is reviewed here.

Articles You May Like

Citizen science programs provide valuable data on intermittent rivers in southwestern US
New drug combination shows promise for common pediatric brain tumor
When it comes to monarchs, fall migration matters
Coral reefs near equator less affected by ocean warming
The recent spread of coyotes across North America did not doom deer populations

Leave a Reply

Your email address will not be published. Required fields are marked *